An evaluation of the clinical effectiveness of autologous bone marrow cells as a supplement to traditional therapy for wound healing in canine: Autologous bone marrow cells for wound healing

Ashish  Kumar; Anil Singh; Sonu  Jaiswal; H.N Singh

doi:10.62310/liab.v5i1.230

Authors

Ashish Kumar Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA
Anil Singh Department of Veterinary clinical complex, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA https://orcid.org/0000-0002-3821-4958
Sonu Jaiswal Department of Veterinary clinical complex, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA
H.N Singh Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA

DOI:

https://doi.org/10.62310/liab.v5i1.230

Keywords:

Canine, Bone marrow cells, Conventional therapy, Healing score, Wound

Abstract

A wound is defined as a breach in the integrity of tissue. Wound healing is an essential requirement of all surgical manipulation, and has the focus of various treatment strategies aimed at enhancing this process. The present retrospective study was carried out with an objective to evaluate the comparative efficacy of local transplantation of autologous whole bone marrow (WBM) in conjunction with conventional therapy versus conventional therapy alone in promoting wound healing in dogs. A total of 14 clinical cases of dogs were randomly selected, irrespective of breed, age, sex, and reproductive status, and divided into two equal groups – Group A and Group B. The dogs in Group A received only conventional wound management, while Group B dogs were treated with local transplantation of autologous WBM along with conventional therapy. The rate of wound healing was accessed on the basis of clinical parameters including appetite, level of activity, visual analogue score (evaluating pain, swelling, and exudation), total healing (on days 0, 3, 7, and 10), and the total number of days required for complete healing/ suture removal. The statistical analysis of the collected data was performed by software SPSS 17, using two-way analysis of variance (ANNOVA). On the basis of clinical findings, it was concluded that addition of local transplant of autologous WBM to conventional wound management therapy significantly increased the quality and rate of wound healing in dogs compared to conventional therapy alone.

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Author Biographies

Ashish Kumar , Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA

Ashish Kumar, PG scholar, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA

Sonu Jaiswal , Department of Veterinary clinical complex, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA

Dr. Sonu Jaiswal, Professor, Department of Veterinary clinical complex, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA

H.N Singh, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA

H.N. Singh, Professor, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Acharya Narendra Deva University of Agriculture and Technology, Ayodhya, (UP)-224 229 INDIA

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