Antimicrobial resistance and antimicrobial activity of plant-based antimicrobial peptides against bacteria: Plant-based antimicrobial peptides

Asif Ali; Silla Ambrose; Dilawar Hussain; Faisal Hafeez; Tayyaba Asghar; Syed Noraiz Arif Shah; Momina Ahsan; Muhammad Shakir; Arsam Ali; Arslan Muhammad Ali Khan; Muhammad Usama Javed

doi:10.62310/liab.v4i2.148

Authors

Asif Ali University of Layyah, Layyah, Pakistan
Silla Ambrose University of Agriculture, Faisalabad, Pakistan https://orcid.org/0009-0004-3189-3689
Dilawar Hussain University of Agriculture, Faisalabad, Pakistan
Faisal Hafeez University of Agriculture, Faisalabad, Pakistan
Tayyaba Asghar University of Veterinary and Animal Sciences, Lahore, Pakistan
Syed Noraiz Arif Shah University of Agriculture, Faisalabad, Pakistan
Momina Ahsan University of Agriculture, Faisalabad, Pakistan
Muhammad Shakir University of Veterinary and Animal Sciences, Lahore, Pakistan https://orcid.org/0009-0001-4904-1562
Arsam Ali Livestock and Dairy Development Department, Punjab, Pakistan
Arslan Muhammad Ali Khan University of Agriculture, Faisalabad, Pakistan https://orcid.org/0009-0001-8292-5810
Muhammad Usama Javed University of Agriculture, Faisalabad, Pakistan https://orcid.org/0009-0009-5051-7247

DOI:

https://doi.org/10.62310/liab.v4i2.148

Keywords:

Antimicrobial peptides, Antibiotic resistance, Mechanism of action, Human Health

Abstract

Antimicrobial peptides (AMPs) are a class of short, usually positively charged, polypeptides which are widely used to overcome the threat of the antimicrobial resistance. The potential of the AMPs is increasing as a new class of antibiotics. They have a broad range of activity against the gram positive bacteria, gram negative bacteria, and fungi. Different kinds of plant based AMPs like thionins, defensins, cyclotides, knottins, snakins and some others are discussed in this review with their potential as antimicrobials – such as regulating plant growth and development and treating many human diseases with a great efficacy. Use of AMPs in agriculture and disease treatment is gaining interest. This review also focuses on the mechanism of action of the AMPs and their potential applications in agriculture and human health.

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