Targeted and efficient therapeutic effect of nanoparticles against malignant tumor: Nanoparticles against tumor

Silla Ambrose; Arslan Muhammad Ali Khan; Iqra  Liaqat; Maham Rub Nawaz; Muhammad Talha  Tariq; Suleman  Masih; Syeda Iqra Basharat; Muhammad Umer Younas Bajwa; Anum  Zufiqar; Laiba Naeem; Muhammad Talha  Talib

doi:10.62310/liab.v5i1.175

Authors

Silla Ambrose Faculty of Veterinary Science, University of Agriculture Faisalabad, Pakistan https://orcid.org/0009-0004-3189-3689
Arslan Muhammad Ali Khan Department of Parasitology, University of Agriculture Faisalabad, Pakistan https://orcid.org/0009-0001-8292-5810
Iqra Liaqat National Institute of Food Science and Technology (NIFSAT), University of Agriculture Faisalabad, Pakistan
Maham Rub Nawaz National Institute of Food Science and Technology (NIFSAT), University of Agriculture Faisalabad, Pakistan https://orcid.org/0009-0002-4657-5216
Muhammad Talha Tariq National Institute of Food Science and Technology (NIFSAT), University of Agriculture Faisalabad, Pakistan https://orcid.org/0009-0007-8384-598X
Suleman Masih Faculty of Allied Health Professionals, Government College University Faisalabad, 38000, Punjab, Pakistan.
Syeda Iqra Basharat Department of Chemistry, Faculty of Sciences, University of Agriculture Faisalabad, Pakistan https://orcid.org/0009-0003-9499-1393
Muhammad Umer Younas Bajwa Department of Chemistry, Faculty of Sciences, University of Agriculture Faisalabad, Pakistan https://orcid.org/0009-0005-3751-4325
Anum Zufiqar Department of Biochemistry, Faculty of Sciences, University of Agriculture Faisalabad, Pakistan https://orcid.org/0009-0009-7659-0741
Laiba Naeem Department of Chemistry, Faculty of Sciences, University of Agriculture Faisalabad, Pakistan
Muhammad Talha Talib Department of Clinical Sciences, University of Veterinary and Animal Sciences Lahore, Jhang Campus, Punjab, Pakistan https://orcid.org/0009-0000-8535-987X

DOI:

https://doi.org/10.62310/liab.v5i1.175

Keywords:

Mutations, Nanoparticles, Alternatives, Treatment, Cancer

Abstract

Cancer or malignant tumors are major global health concerns and limited treatment regimens are hazardous threats to people. Mostly malignant tumors are caused by various genetic and environmental factors. Various chemical agents have been used over the years to treat and limit this disease but due to unsatisfactory and insufficient results, researchers have diverted their attention towards alternatives. Nanoparticles (NPs) have a major role in improving treatment facilities. Nanoparticles have peculiar characteristics due to their size, shape, charge, and surface area. Their unique properties allow improved drug delivery to the target site at the cellular level by active or passive targeting. Different NPs are being modified for cancer therapy like polymeric NPs, liposomes, extracellular vesicles, nano-emulsions, carbon NPs, quantum dots, magnetic NPs, and silica NPs. They hold a promising future for diagnosis, treatment, and lowering the risk of these lethal diseases including breast and brain cancer due to their various beneficial mechanisms of overcoming drug resistance mechanisms.

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